ACT NOW:

Give your eligible ARPI-naïve

mCRPC patients the chance to

benefit from LYNPARZA

(olaparib) combination1

Visit LYNPARZA.co.uk

This link will take you to an AZ/MSD promotional website
where products will be mentioned.

LYNPARZA tablets are indicated: in combination with abiraterone
and prednisone/prednisolone for the treatment of adult patients with
mCRPC in whom chemotherapy is not clinically indicated.2

ARPI=androgen receptor pathway inhibitor; mCRPC=metastatic castration-
resistant prostate cancer. 1. Clarke NW, et al. NEJM Evid.2022;1(9):doi:10.1056/
EVIDoa2200043; 2. LYNPARZA (olaparib). Summary of Product Characteristics.

For UK Healthcare Professionals only. This promotional asset has been fully
developed and funded by AstraZeneca and MSD. Click here for UK
prescribing information and adverse event reporting information.

GB-70322 | October 2025

MSD - AstraZeneca

CHALLENGE
EXPECATIONS:

LYNPARZA combination is the first PARPi

+ ARPI reimbursed for the treatment

of adult patients with mCRPC, in whom

chemotherapy is not clinically indicated1,2

ARPI=androgen receptor pathway inhibitor; mCRPC=metastatic castration-
resistant prostate cancer; PARPi=Poly(ADP-ribose) polymerase inhibitor.
1. Olaparib with abiraterone for untreated hormone relapsed metastatic
prostate cancer. NICE TA951. February 2024. https://www.nice.org.uk/
guidance/ta951
. Accessed October 2025; 2. Scottish Medicines Consortium.
Olaparib (Lynparza) March 2024. Available at: https://
www.scottishmedicines.org.uk/medicines-advice/olaparib-lynparza-mcrpc-
full-smc2617/
Accessed October 2025.

For UK healthcare professionals only. This promotional asset has been fully
developed and funded by AstraZeneca and MSD. Click here for UK
prescribing information and adverse event reporting information.

GB-70322 | October 2025

MSD - AstraZeneca

CONSIDER
LYNPARZA
COMBINATION:

For all your eligible
ARPI-naïve mCRPC
patients, irrespective
of HRRm status1,2

ARPI=androgen receptor pathway inhibitor; HRRm=homologous
recombination repair mutation; mCRPC=metastatic castration-resistant
prostate cancer. 1. LYNPARZA (olaparib). Summary of Product Characteristics;
2. Clarke NW, et al. NEJM Evid.2022;1(9):doi:10.1056/EVIDoa2200043.

For UK healthcare professionals only. This promotional asset has been fully
developed and funded by AstraZeneca and MSD. Click here for UK
prescribing information and adverse event reporting information.

GB-70322 | October 2025

MSD - AstraZeneca