WAINUA may cause side effects, including:

• Low vitamin A level, which is a serious, but common side effect of treatment with WAINUA. Your doctor should tell you to take vitamin A supplements. Do not take more than the amount of vitamin A your doctor has recommended. Call your doctor if you develop eye problems such as difficulty seeing at night or in low-lit areas (night blindness), or dry eyes. If you develop eye problems, your doctor should refer you to an eye doctor

The most common side effects include decreased vitamin A and vomiting.

Before you take WAINUA, tell your healthcare provider:

• if you are pregnant or breastfeeding, or plan to become pregnant or breastfeed. It is not known if WAINUA can harm your baby. Changes in vitamin A levels and vitamin A supplementation related to use of WAINUA may harm your unborn baby. It is not known if WAINUA passes into breast milk
• about all the medicines you take, including prescription and nonprescription medicines, vitamins, and herbal supplements. Especially tell your healthcare provider if you take vitamin A or beta-carotene supplements

APPROVED USES

WAINUA injection, for subcutaneous use, 45 mg is a prescription medicine used to treat adults with polyneuropathy of hereditary transthyretin-mediated amyloidosis.

Please see full Prescribing Information, including Patient Information.

You may report side effects related to AstraZeneca
products.

WAINUA^TM is a trademark of the AstraZeneca group of companies.

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US-85394
Last Updated 5/24