TREMFYA® (guselkumab) is indicated for the treatment of adult patients with moderately to severely active Crohn’s disease who have had an inadequate response, lost response, or were intolerant to either conventional therapy or a biologic treatment.3 TREMFYA® is indicated for the treatment of adult patients with moderately to severely active ulcerative colitis who have had an inadequate response, lost response or were intolerant to either conventional therapy, a biologic treatment, or a Janus kinase (JAK) inhibitor.3

Information about this product, including side effects, precautions, contraindications and dosing and administration can be found at https://www.janssen-pi.co.uk/tremfya. Prescribers are recommended to consult the summary of product characteristics before prescribing.

Abbreviations: NICE, National Institute for Health and Care Excellence; JAK, Janus Kinase Inhibitor

References: 1.© National Institute for Health and Care Excellence [2025]. Guselkumab for previously treated moderately to severely active Crohn's disease [TA11245]. Available from https://www.nice.org.uk/guidance/ta1095/chapter/1-Recommendations.
All rights reserved. Subject to Notice of rights 2. © National Institute for Health and Care Excellence [2025]. Guselkumab for treating moderately to severely active ulcerative colitis [TA11247]. Available from https://www.nice.org.uk/guidance/ta1094/chapter/1-Recommendations. 3. TREMFYA® (guselkumab) Summary of Product Characteristics.

NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.
Adverse events associated with a Janssen/Johnson & Johnson company product should be reported. Reporting forms and information can be found at yellowcard.mhra.gov.uk or search for MHRA Yellow Card in the Google Play or Apple App Store. Adverse events should also be reported to Johnson & Johnson’s Drug Safety Department on 01494 567447 or at dsafety@its.jnj.com.
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For UK healthcare professionals only.
For UK healthcare professionals only.